The first headband for home-use that enables closed-loop acoustic stimulation of EEG Slow Oscillations during sleep to improve memory
The ability to store, maintain, and retrieve memories is indispensable for all human endeavors, from childhood to old age, and is critical to maintaining well-being, productivity in career and personal life. Consolidation of hippocampal-dependent declarative memory is orchestrated in part by slow waves or slow oscillations (SOs), which are slow (less than 1 Hz), high amplitude (80 µV or greater) EEG oscillations that are produced during the deepest levels of sleep. Enhancement of these SOs through audio stimulation has shown to improve memory in a number of studies. However, technological challenges have prevented the translation of this lab-proven method to the community for home use. NeuroGeneces will develop Memorise, a low-costwearable device to improve memory performance during sleep. The key innovation of the product will be Machine Learning algorithms that personalize the enhancement of SOs. It consists of a high- and individually-tailored quality memory enhancement which reduces potential harm to consumers from side effects of nootropics and prescription drugs. Memorise also allows the translation of lab benefits into at-home, widespread use. Successfully translating lab-proven technology to improve memory via audio stimulation into a comfortable and easy-to-use wearable sleep headband will provide the first scientifically proven effective and safe product to the memory enhancement consumer market.